PDB entry 2q1j

View 2q1j on RCSB PDB site
Description: The discovery of glycine and related amino acid-based factor xa inhibitors
Class: hydrolase
Keywords: COAGULATION FXA, Blood coagulation, Calcium, Cleavage on pair of basic residues, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Hydroxylation, Polymorphism, Protease, Serine protease, Zymogen
Deposited on 2007-05-24, released 2007-08-14
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.23
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Activated factor Xa heavy chain (EC 3.4.21.6)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2q1ja_
  • Chain 'B':
    Compound: Factor X light chain (EC 3.4.21.6)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2q1jb_
  • Heterogens: CA, FXI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2q1jA (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2q1jB (B:)
    lcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle