PDB entry 2pzu

View 2pzu on RCSB PDB site
Description: Crystal structure of Staphylococcal nuclease variant V66N/P117G/H124L/S128A at cryogenic temperature
Class: hydrolase
Keywords: Staphylococcal nuclease, nuclease, hyperstable variant, internal waters, hydrolase
Deposited on 2007-05-18, released 2008-05-20
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.211
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thermonuclease
    Species: STAPHYLOCOCCUS AUREUS
    Gene: nuc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NXI6
      • engineered (65)
      • engineered (116)
      • engineered (127)
    Domains in SCOPe 2.05: d2pzua_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2pzuA (A:)
    atstkklhkepatlikaidgdtvklmykgqpmtfrlllvdtpetkhpkkgvekygpeasa
    ftkkmnenakkievefdkgqrtdkygrglayiyadgkmvnealvrqglakvayvykgnnt
    heqllrkaeaqakkeklniwsednadsgq
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pzuA (A:)
    lhkepatlikaidgdtvklmykgqpmtfrlllvdtpetkvekygpeasaftkkmnenakk
    ievefdkgqrtdkygrglayiyadgkmvnealvrqglakvayvykgnntheqllrkaeaq
    akkeklniws