PDB entry 2pxi

View 2pxi on RCSB PDB site
Description: Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate
Class: lyase, transferase/DNA
Keywords: Nucleotidyl Transferase, DNA polymerase, chiral Interaction, stereoselectivity, LYASE, TRANSFERASE/DNA COMPLEX
Deposited on 2007-05-14, released 2008-01-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.206
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2pxia1, d2pxia2, d2pxia3
  • Chain 'D':
    Compound: 5'-d(p*gp*tp*cp*gp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*(doc))-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*gp*ap*cp*cp*gp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3'
  • Heterogens: MG, NA, CL, GFH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2pxiA (A:)
    mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
    klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
    tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
    frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
    lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
    lgvtgvageplpvdsekdifdyiqwkyrepkdrse
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pxiA (A:)
    tlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtki
    aekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktledlrkne
    dklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrgaessg
    dmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpskndeke
    yphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvtgvage
    plpvdsekdifdyiqwkyrepkdrse
    

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.