PDB entry 2pvv

View 2pvv on RCSB PDB site
Description: Structure of human glutamate carboxypeptidase II (GCPII) in complex with L-serine-O-sulfate
Class: Hydrolase
Keywords: prostate specific membrane antigen; metallopeptidase; folate hydrolase; glutamate carboxypeptidase II; Naaladase; L-serine-O-sulfate; L-SOS
Deposited on 2007-05-10, released 2007-05-22
The last revision prior to the SCOP 1.73 freeze date was dated 2007-08-14, with a file datestamp of 2007-08-10.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: 0.176
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutamate carboxypeptidase 2
    Species: HOMO SAPIENS
    Gene: FOLH1, FOLH, NAALAD1, PSM, PSMA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2pvva1, d2pvva2, d2pvva3
  • Heterogens: NAG, ZN, CA, CL, OSE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pvvA (A:)
rskssneatnitpkhnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwk
efgldsvelahydvllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppf
safspqgmpegdlvyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlag
akgvilysdpadyfapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrr
giaeavglpsipvhpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqk
vkmhihstnevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrs
fgtlkkegwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnyt
lrvdctplmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndf
evffqrlgiasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrg
gmvfelansivlpfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfte
iaskfserlqdfdksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkya
gesfpgiydalfdieskvdpskawgevkrqiyvaaftvqaaaetlseva

    Sequence, based on observed residues (ATOM records): (download) 
    >2pvvA (A:)
khnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahyd
vllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdl
vyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpady
fapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipv
hpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvkmhihstnevtr
iynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkkegwrprr
tilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctplmyslv
hnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrlgiasgr
arytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivlp
fdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdfs
npivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalfdie
skvdpskawgevkrqiyvaaftvqaaaetlseva