PDB entry 2pvs

View 2pvs on RCSB PDB site
Description: Structure of human pancreatic lipase related protein 2 mutant N336Q
Class: hydrolase
Keywords: Lipase, galacto lipids hydrolysis, HYDROLASE
Deposited on 2007-05-10, released 2007-12-18
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-01-20, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.193
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pancreatic lipase-related protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PNLIPRP2, PLRP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54317 (0-451)
      • engineered (335)
    Domains in SCOPe 2.06: d2pvsa1, d2pvsa2
  • Chain 'B':
    Compound: Pancreatic lipase-related protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PNLIPRP2, PLRP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54317 (0-451)
      • engineered (335)
    Domains in SCOPe 2.06: d2pvsb1, d2pvsb2
  • Heterogens: SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2pvsA (A:)
    kevcygqlgcfsdekpwagtlqrpvkllpwspedidtrfllytnenpnnfqlitgtepdt
    ieasnfqldrktrfiihgfldkaedswpsdmckkmfevekvncicvdwrhgsramytqav
    qnirvvgaetafliqalstqlgysledvhvighslgahtaaeagrrlggrvgritgldpa
    gpcfqdepeevrldpsdavfvdvihtdsspivpslgfgmsqkvghldffpnggkempgck
    knvlstitdidgiwegiggfvscnhlrsfeyysssvlnpdgflgypcasydefqeskcfp
    cpaegcpkmghyadqfkgktsaveqtfflntgesgqftswrykvsvtlsgkekvngyiri
    alygsnenskqyeifkgslkpdashtcaidvdfnvgkiqkvkflwnkrginlsepklgas
    qitvqsgedgteynfcssdtveenvlqslypc
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pvsA (A:)
    kevcygqlgcfsdekpwagtlqrpvkllpwspedidtrfllytnenpnnfqlitgtepdt
    ieasnfqldrktrfiihgfldkaedswpsdmckkmfevekvncicvdwrhgsramytqav
    qnirvvgaetafliqalstqlgysledvhvighslgahtaaeagrrlggrvgritgldpa
    gpcfqdepeevrldpsdavfvdvihtdsspivpslgfgmsqkvghldffpnggkempgck
    egiggfvscnhlrsfeyysssvlnpdgflgypcasydefqeskcfpcpaegcpkmghyad
    qfkgktsaveqtfflntgesgqftswrykvsvtlsgkekvngyirialygsnenskqyei
    fkgslkpdashtcaidvdfnvgkiqkvkflwnknlsepklgasqitvqsgedgteynfcs
    sdtveenvlqslypc
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2pvsB (B:)
    kevcygqlgcfsdekpwagtlqrpvkllpwspedidtrfllytnenpnnfqlitgtepdt
    ieasnfqldrktrfiihgfldkaedswpsdmckkmfevekvncicvdwrhgsramytqav
    qnirvvgaetafliqalstqlgysledvhvighslgahtaaeagrrlggrvgritgldpa
    gpcfqdepeevrldpsdavfvdvihtdsspivpslgfgmsqkvghldffpnggkempgck
    knvlstitdidgiwegiggfvscnhlrsfeyysssvlnpdgflgypcasydefqeskcfp
    cpaegcpkmghyadqfkgktsaveqtfflntgesgqftswrykvsvtlsgkekvngyiri
    alygsnenskqyeifkgslkpdashtcaidvdfnvgkiqkvkflwnkrginlsepklgas
    qitvqsgedgteynfcssdtveenvlqslypc
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pvsB (B:)
    kevcygqlgcfsdekpwagtlqrpvkllpwspedidtrfllytnenpnnfqlitgtepdt
    ieasnfqldrktrfiihgfldkaedswpsdmckkmfevekvncicvdwrhgsramytqav
    qnirvvgaetafliqalstqlgysledvhvighslgahtaaeagrrlggrvgritgldpa
    gpcfqdepeevrldpsdavfvdvihtdsspivpslgfgmsqkvghldffpnggkempgck
    knidgiwegiggfvscnhlrsfeyysssvlnpdgflgypcasydefqeskcfpcpaegcp
    kmghyadqfkgktsaveqtfflntgesgqftswrykvsvtlsgkekvngyirialygsne
    nskqyeifkgslkpdashtcaidvdfnvgkiqkvkflwnkrginlsepklgasqitvqsg
    edgteynfcssdtveenvlqslypc