PDB entry 2puq

View 2puq on RCSB PDB site
Description: Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
Class: hydrolase/hydrolase inhibitor
Keywords: active site inhibitor, blood clotting, hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2007-05-09, released 2007-05-22
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.231
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Coagulation factor VII
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2puqh_
  • Chain 'I':
    Compound: trp-tyr-thr-arg chloromethylketone inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 2PUQ (Start-4)
  • Chain 'L':
    Compound: Coagulation factor VII
    Species: Homo sapiens [TaxId:9606]
    Gene: F7
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: tissue factor
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BGC, FUC, CA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2puqH (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
    sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
    seprpgvllrapfp
    

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'T':
    No sequence available.