PDB entry 2pqk

View 2pqk on RCSB PDB site
Description: X-ray crystal structure of human Mcl-1 in complex with Bim BH3
Class: apoptosis
Keywords: Bcl-2 family, BH3 domain, APOPTOSIS
Deposited on 2007-05-02, released 2007-06-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-04-10, with a file datestamp of 2013-04-05.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.196
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2pqka_
  • Chain 'B':
    Compound: Bim BH3 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2PQK
  • Heterogens: ZN, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2pqkA (A:)
    gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
    gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
    laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pqkA (A:)
    delyrqsleiisrylreqatgakdtkgatsrkaletlrrvgdgvqrnhetafqgmlrkld
    ikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitd
    vlvrtkrdwlvkqrgwdgfveffhv
    

  • Chain 'B':
    No sequence available.