PDB entry 2pqk
View 2pqk on RCSB PDB site
Description: X-ray crystal structure of human Mcl-1 in complex with Bim BH3
Class: apoptosis
Keywords: Bcl-2 family, BH3 domain, APOPTOSIS
Deposited on
2007-05-02, released
2007-06-19
The last revision prior to the SCOPe 2.03 freeze date was dated
2013-04-10, with a file datestamp of
2013-04-05.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.196
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
Species: Homo sapiens [TaxId:9606]
Gene: MCL1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d2pqka_ - Chain 'B':
Compound: Bim BH3 peptide
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: ZN, NA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2pqkA (A:)
gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg
Sequence, based on observed residues (ATOM records): (download)
>2pqkA (A:)
delyrqsleiisrylreqatgakdtkgatsrkaletlrrvgdgvqrnhetafqgmlrkld
ikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitd
vlvrtkrdwlvkqrgwdgfveffhv
- Chain 'B':
No sequence available.