PDB entry 2pqa

View 2pqa on RCSB PDB site
Description: Crystal Structure of Full-length Human RPA 14/32 Heterodimer
Class: replication
Keywords: RPA14/32; ssDNA binding protein; OB-fold, REPLICATION
Deposited on 2007-05-01, released 2007-11-13
The last revision prior to the SCOP 1.75 freeze date was dated 2009-01-06, with a file datestamp of 2009-01-02.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.231
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pqaa1
  • Chain 'B':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pqab1
  • Chain 'C':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pqac1
  • Chain 'D':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pqad1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2pqaA (A:)
    raqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaap
    mdvrqwvdtddtssentvvppetyvkvaghlrsfqnkkslvafkimpledmneftthile
    vinahmvlska
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pqaA (A:)
    raqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaap
    mdvrqwvdtddtstvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevin
    ahmvlska
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2pqaB (B:)
    mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
    mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
    neavkiihdfpqfyplgivqhd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pqaB (B:)
    dmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmepldee
    isgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2pqaC (C:)
    raqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaap
    mdvrqwvdtddtssentvvppetyvkvaghlrsfqnkkslvafkimpledmneftthile
    vinahmvlska
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pqaC (C:)
    qhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaapmd
    vrqwvdtddtssentvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevi
    nahmvls
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2pqaD (D:)
    mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
    mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
    neavkiihdfpqfyplgivqhd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2pqaD (D:)
    mmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmepldeei
    sgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgi