PDB entry 2po7

View 2po7 on RCSB PDB site
Description: Crystal structure of human ferrochelatase mutant with His 341 replaced by Cys
Class: lyase
Keywords: ferrochelatase; h341c; fe2s2 cluster; heme biosynthesis; protoheme; ferro-lyase; mature length; proteolytically processed mitochondrial inner membrane protein, lyase
Deposited on 2007-04-25, released 2007-10-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ferrochelatase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: FECH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22830 (0-358)
      • engineered (31)
      • engineered (50)
      • engineered (276)
    Domains in SCOPe 2.07: d2po7a_
  • Chain 'B':
    Compound: Ferrochelatase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: FECH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22830 (0-358)
      • engineered (31)
      • engineered (50)
      • engineered (276)
    Domains in SCOPe 2.07: d2po7b_
  • Heterogens: FES, CHD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2po7A (A:)
rkpktgilmlnmggpetlgdvhdfllrlfldqdlmtlpiqnklapfiakrltpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadhilke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdcietlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2po7B (B:)
rkpktgilmlnmggpetlgdvhdfllrlfldqdlmtlpiqnklapfiakrltpkiqeqyr
rigggspikiwtskqgegmvklldelspntaphkyyigfryvhplteeaieemerdgler
aiaftqypqyscsttgsslnaiyryynqvgrkptmkwstidrwpthhlliqcfadhilke
ldhfplekrsevvilfsahslpmsvvnrgdpypqevsatvqkvmerleycnpyrlvwqsk
vgpmpwlgpqtdesikglcergrknillvpiaftsdcietlyeldieysqvlakecgven
irraeslngnplfskaladlvhshiqsnelcskqltlscplcvnpvcretksfftsqql