PDB entry 2pnr

View 2pnr on RCSB PDB site
Description: Crystal Structure of the asymmetric Pdk3-l2 Complex
Class: transferase
Keywords: pyruvate dehydrogenase kinase 3, lipoyl-bearing domain, asymmetric protein-protein complex, TRANSFERASE
Deposited on 2007-04-25, released 2007-08-21
The last revision prior to the SCOP 1.75 freeze date was dated 2007-08-21, with a file datestamp of 2007-08-17.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.176
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3
    Species: HOMO SAPIENS
    Gene: PDK3
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pnra1, d2pnra2
  • Chain 'B':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3
    Species: HOMO SAPIENS
    Gene: PDK3
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pnrb1, d2pnrb2
  • Chain 'C':
    Compound: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
    Species: HOMO SAPIENS
    Gene: DLAT, DLTA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pnrc1
  • Chain 'E':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3
    Species: HOMO SAPIENS
    Gene: PDK3
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pnre1, d2pnre2
  • Chain 'F':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3
    Species: HOMO SAPIENS
    Gene: PDK3
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pnrf1, d2pnrf2
  • Chain 'G':
    Compound: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
    Species: HOMO SAPIENS
    Gene: DLAT, DLTA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pnrg1
  • Heterogens: RED, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pnrA (A:)
ggshhhhhhgmarlenlyfqgkqpvpkqierysrfspsplsikqfldfgrdnacektsym
flrkelpvrlantmrevnllpdnllnrpsvglvqswymqsflelleyenkspedpqvldn
flqvlikvrnrhndvvptmaqgvieykekfgfdpfistniqyfldrfytnrisfrmlinq
htllfggdtnpvhpkhigsidptcnvadvvkdayetakmlceqyylvapeleveefnaka
pdkpiqvvyvpshlfhmlfelfknsmratvelyedrkegypavktlvtlgkedlsikisd
lgggvplrkidrlfnymystaprpsleptraaplagfgyglpisrlyaryfqgdlklysm
egvgtdaviylkalssesferlpvfnksawrhykttpeaddwsnpsseprdaskykakq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pnrA (A:)
pkqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnll
nrpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgvie
ykekfgfdpfistniqyfldrfytnrisfrmlinqhtllfggdtnpvhpkhigsidptcn
vadvvkdayetakmlceqyylvapeleveefnakapdkpiqvvyvpshlfhmlfelfkns
mratvelyedrkegypavktlvtlgkedlsikisdlgggvplrkidrlfnyaaplagfgy
glpisrlyaryfqgdlklysmegvgtdaviylkalssesferlpvfnksawrhykttpea
ddwsnpsseprdas

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pnrB (B:)
ggshhhhhhgmarlenlyfqgkqpvpkqierysrfspsplsikqfldfgrdnacektsym
flrkelpvrlantmrevnllpdnllnrpsvglvqswymqsflelleyenkspedpqvldn
flqvlikvrnrhndvvptmaqgvieykekfgfdpfistniqyfldrfytnrisfrmlinq
htllfggdtnpvhpkhigsidptcnvadvvkdayetakmlceqyylvapeleveefnaka
pdkpiqvvyvpshlfhmlfelfknsmratvelyedrkegypavktlvtlgkedlsikisd
lgggvplrkidrlfnymystaprpsleptraaplagfgyglpisrlyaryfqgdlklysm
egvgtdaviylkalssesferlpvfnksawrhykttpeaddwsnpsseprdaskykakq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pnrB (B:)
kqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnlln
rpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgviey
kekstniqyfldrfytnrisfrmlinqhtllfggdtnpvhpkhigsidptcnvadvvkda
yetakmlceqyylvapeleveefnakapdkpiqvvyvpshlfhmlfelfknsmratvely
edypavktlvtlgkedlsikisdlgggvplrkidrlfnymglpisrlyaryfqgdlklys
megvgtdaviylkalssesferlpvfnksawrhyktaddws

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pnrC (C:)
ggshhhhhhgmarlenlyfqgssypphmqvllpalsptmtmgtvqrwekkvgeklsegdl
laeietdkatigfevqeegylakilvpegtrdvplgtplciivekeadisafadyrptev
tdlkpqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >2pnrC (C:)
vllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegylakilvpeg
trdvplgtplciivekead

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2pnrE (E:)
ggshhhhhhgmarlenlyfqgkqpvpkqierysrfspsplsikqfldfgrdnacektsym
flrkelpvrlantmrevnllpdnllnrpsvglvqswymqsflelleyenkspedpqvldn
flqvlikvrnrhndvvptmaqgvieykekfgfdpfistniqyfldrfytnrisfrmlinq
htllfggdtnpvhpkhigsidptcnvadvvkdayetakmlceqyylvapeleveefnaka
pdkpiqvvyvpshlfhmlfelfknsmratvelyedrkegypavktlvtlgkedlsikisd
lgggvplrkidrlfnymystaprpsleptraaplagfgyglpisrlyaryfqgdlklysm
egvgtdaviylkalssesferlpvfnksawrhykttpeaddwsnpsseprdaskykakq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pnrE (E:)
pkqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnll
nrpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgvie
ykekfgfdpfistniqyfldrfytnrisfrmlinqhtllfggdtnpvhpkhigsidptcn
vadvvkdayetakmlceqyylvapeleveefnakapdkpiqvvyvpshlfhmlfelfkns
mratvelyedrkegypavktlvtlgkedlsikisdlgggvplrkidrlfnyaaplagfgy
glpisrlyaryfqgdlklysmegvgtdaviylkalssesferlpvfnksawrhykttpea
ddwsnpsseprdas

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2pnrF (F:)
ggshhhhhhgmarlenlyfqgkqpvpkqierysrfspsplsikqfldfgrdnacektsym
flrkelpvrlantmrevnllpdnllnrpsvglvqswymqsflelleyenkspedpqvldn
flqvlikvrnrhndvvptmaqgvieykekfgfdpfistniqyfldrfytnrisfrmlinq
htllfggdtnpvhpkhigsidptcnvadvvkdayetakmlceqyylvapeleveefnaka
pdkpiqvvyvpshlfhmlfelfknsmratvelyedrkegypavktlvtlgkedlsikisd
lgggvplrkidrlfnymystaprpsleptraaplagfgyglpisrlyaryfqgdlklysm
egvgtdaviylkalssesferlpvfnksawrhykttpeaddwsnpsseprdaskykakq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pnrF (F:)
kqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnlln
rpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgviey
kekstniqyfldrfytnrisfrmlinqhtllfggdtnpvhpkhigsidptcnvadvvkda
yetakmlceqyylvapeleveefnakapdkpiqvvyvpshlfhmlfelfknsmratvely
edypavktlvtlgkedlsikisdlgggvplrkidrlfnymglpisrlyaryfqgdlklys
megvgtdaviylkalssesferlpvfnksawrhyktaddws

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2pnrG (G:)
ggshhhhhhgmarlenlyfqgssypphmqvllpalsptmtmgtvqrwekkvgeklsegdl
laeietdkatigfevqeegylakilvpegtrdvplgtplciivekeadisafadyrptev
tdlkpqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >2pnrG (G:)
vllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegylakilvpeg
trdvplgtplciivekead