PDB entry 2pjy

View 2pjy on RCSB PDB site
Description: Structural basis for cooperative assembly of the TGF-beta signaling complex
Class: cytokine/cytokine receptor
Keywords: ternary complex, three finger toxin, CYTOKINE-CYTOKINE RECEPTOR COMPLEX
Deposited on 2007-04-16, released 2008-02-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.244
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transforming growth factor beta-3
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFB3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2pjya_
  • Chain 'B':
    Compound: TGF-beta receptor type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37173 (0-107)
      • engineered (0)
    Domains in SCOPe 2.06: d2pjyb_
  • Chain 'C':
    Compound: TGF-beta receptor type-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36897 (0-78)
      • engineered (37)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2pjyA (A:)
aldtnycfrnleenccvrplyidfrqdlgwkwvhepkgyyanfcsgpcpylrsadtthst
vlglyntlnpeasaspccvpqdlepltilyyvgrtpkveqlsnmvvksckcs

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2pjyB (B:)
agavkfpqlckfcdvrfstcdnqkscmsncsitsicekpqevcvavwrkndenitletvc
hdpklpyhdfiledaaspkcimkekkkpgetffmcscssdecndniif

  • Chain 'C':
    No sequence available.