PDB entry 2pi2

View 2pi2 on RCSB PDB site
Description: Full-length Replication protein A subunits RPA14 and RPA32
Class: replication, DNA binding protein
Keywords: full-length RPA14/32, ssDNA binding protein, OB-fold, Dioxane, REPLICATION, DNA BINDING PROTEIN
Deposited on 2007-04-12, released 2007-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.233
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2a_
  • Chain 'B':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2b_
  • Chain 'C':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2c_
  • Chain 'D':
    Compound: Replication protein A 32 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA2, REPA2, RPA32
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2d_
  • Chain 'E':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2e_
  • Chain 'F':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2f_
  • Chain 'G':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2g_
  • Chain 'H':
    Compound: Replication protein A 14 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: RPA3, REPA3, RPA14
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pi2h_
  • Heterogens: DIO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pi2A (A:)
mwnsgfesygsssyggaggytqspggfgspapsqaekksraraqhivpctisqllsatlv
devfrignveisqvtivgiirhaekaptnivykiddmtaapmdvrqwvdtddtssentvv
ppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlskansqpsagr
apisnpgmseagnfggnsfmpangltvaqnqvlnlikacprpeglnfqdlknqlkhmsvs
sikqavdflsneghiystvdddhfkstdae

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2A (A:)
araqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaa
pmdvrqwvdntvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahm
vlskansqp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pi2B (B:)
mwnsgfesygsssyggaggytqspggfgspapsqaekksraraqhivpctisqllsatlv
devfrignveisqvtivgiirhaekaptnivykiddmtaapmdvrqwvdtddtssentvv
ppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlskansqpsagr
apisnpgmseagnfggnsfmpangltvaqnqvlnlikacprpeglnfqdlknqlkhmsvs
sikqavdflsneghiystvdddhfkstdae

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2B (B:)
raqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaap
mdvrqwvtvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvls
kans

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pi2C (C:)
mwnsgfesygsssyggaggytqspggfgspapsqaekksraraqhivpctisqllsatlv
devfrignveisqvtivgiirhaekaptnivykiddmtaapmdvrqwvdtddtssentvv
ppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlskansqpsagr
apisnpgmseagnfggnsfmpangltvaqnqvlnlikacprpeglnfqdlknqlkhmsvs
sikqavdflsneghiystvdddhfkstdae

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2C (C:)
aqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaapm
dvrqwvsentvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmv
lskan

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2pi2D (D:)
mwnsgfesygsssyggaggytqspggfgspapsqaekksraraqhivpctisqllsatlv
devfrignveisqvtivgiirhaekaptnivykiddmtaapmdvrqwvdtddtssentvv
ppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlskansqpsagr
apisnpgmseagnfggnsfmpangltvaqnqvlnlikacprpeglnfqdlknqlkhmsvs
sikqavdflsneghiystvdddhfkstdae

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2D (D:)
aqhivpctisqllsatlvdevfrignveisqvtivgiirhaekaptnivykiddmtaapm
dvrqwvtvvppetyvkvaghlrsfqnkkslvafkimpledmneftthilevinahmvlsk
ans

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2pi2E (E:)
mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
neavkiihdfpqfyplgivqhd

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2E (E:)
vdmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmeplde
eisgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgiv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2pi2F (F:)
mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
neavkiihdfpqfyplgivqhd

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2F (F:)
vdmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmeplde
eisgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgivqh

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2pi2G (G:)
mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
neavkiihdfpqfyplgivqhd

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2G (G:)
vdmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmeplde
eisgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgivq

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2pi2H (H:)
mghhhhhhhhhhssghiegrhmvdmmdlprsrinagmlaqfidkpvcfvgrlekihptgk
mfilsdgegkngtielmepldeeisgivevvgrvtakatilctsyvqfkedshpfdlgly
neavkiihdfpqfyplgivqhd

    Sequence, based on observed residues (ATOM records): (download) 
    >2pi2H (H:)
vdmmdlprsrinagmlaqfidkpvcfvgrlekihptgkmfilsdgegkngtielmeplde
eisgivevvgrvtakatilctsyvqfkedshpfdlglyneavkiihdfpqfyplgiv