PDB entry 2phb

View 2phb on RCSB PDB site
Description: An Orally Efficacious Factor Xa Inhibitor
Class: blood clotting
Keywords: fxa coagulation factor inhibitor, blood clotting
Deposited on 2007-04-10, released 2008-03-25
The last revision prior to the SCOP 1.75 freeze date was dated 2008-03-25, with a file datestamp of 2008-03-21.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.26
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: coagulation factor x, heavy chain
    Species: HOMO SAPIENS
    Gene: F10
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2phba1
  • Chain 'B':
    Compound: coagulation factor x, light chain
    Species: HOMO SAPIENS
    Gene: F10
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2phbb1
  • Heterogens: CA, 230, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2phbA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2phbB (B:)
lcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle