PDB entry 2pbj

View 2pbj on RCSB PDB site
Description: GSH-heme bound microsomal prostaglandin E synthase
Class: isomerase, lyase
Keywords: Prostaglandin E synthase, GSH-heme bound enzyme, Dual function enzyme, ISOMERASE, LYASE
Deposited on 2007-03-28, released 2008-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.242
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin E synthase 2
    Species: Macaca fascicularis [TaxId:9541]
    Gene: mPGES-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pbja1, d2pbja2
  • Chain 'B':
    Compound: Prostaglandin E synthase 2
    Species: Macaca fascicularis [TaxId:9541]
    Gene: mPGES-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pbjb1, d2pbjb2
  • Chain 'C':
    Compound: Prostaglandin E synthase 2
    Species: Macaca fascicularis [TaxId:9541]
    Gene: mPGES-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pbjc1, d2pbjc2
  • Chain 'D':
    Compound: Prostaglandin E synthase 2
    Species: Macaca fascicularis [TaxId:9541]
    Gene: mPGES-2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2pbjd1, d2pbjd2
  • Heterogens: CL, HEM, GSH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pbjA (A:)
ersavqlslssrlqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrk
vpilvaqegessqqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgn
kywlmlnekeaqqvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivre
gkfgavegavakymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmgg
qkpnladlavygvlrvmegldafddlmqhthiqpwylrveraiteaspah

    Sequence, based on observed residues (ATOM records): (download) 
    >2pbjA (A:)
lqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrkvpilvaqegess
qqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgnkywlmlnekeaq
qvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivregkfgavegavak
ymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmggqkpnladlavyg
vlrvmegldafddlmqhthiqpwylrveraitea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pbjB (B:)
ersavqlslssrlqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrk
vpilvaqegessqqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgn
kywlmlnekeaqqvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivre
gkfgavegavakymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmgg
qkpnladlavygvlrvmegldafddlmqhthiqpwylrveraiteaspah

    Sequence, based on observed residues (ATOM records): (download) 
    >2pbjB (B:)
lqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrkvpilvaqegess
qqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgnkywlmlnekeaq
qvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivregkfgavegavak
ymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmggqkpnladlavyg
vlrvmegldafddlmqhthiqpwylrveraitea

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pbjC (C:)
ersavqlslssrlqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrk
vpilvaqegessqqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgn
kywlmlnekeaqqvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivre
gkfgavegavakymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmgg
qkpnladlavygvlrvmegldafddlmqhthiqpwylrveraiteaspah

    Sequence, based on observed residues (ATOM records): (download) 
    >2pbjC (C:)
lqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrkvpilvaqegess
qqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgnkywlmlnekeaq
qvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivregkfgavegavak
ymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmggqkpnladlavyg
vlrvmegldafddlmqhthiqpwylrveraitea

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2pbjD (D:)
ersavqlslssrlqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrk
vpilvaqegessqqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgn
kywlmlnekeaqqvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivre
gkfgavegavakymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmgg
qkpnladlavygvlrvmegldafddlmqhthiqpwylrveraiteaspah

    Sequence, based on observed residues (ATOM records): (download) 
    >2pbjD (D:)
lqltlyqyktcpfcskvrafldfhalpyqvvevnpvlraeikfssyrkvpilvaqegess
qqlndssviisalktylvsgqpleeiityypamkavndqgkevtefgnkywlmlnekeaq
qvysgkearteemkwrqwaddwlvhlispnvyrtptealasfdyivregkfgavegavak
ymgaaamyliskrlksrhrlqdnvredlyeaadkwvaavgkdrpfmggqkpnladlavyg
vlrvmegldafddlmqhthiqpwylrveraitea