PDB entry 2pam

View 2pam on RCSB PDB site
Description: Structure of a H49N, H51N double mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus complexed with TDP
Class: isomerase
Keywords: deoxysugar biosynthesis, S-Layer biosynthesis, ketoisomerase
Deposited on 2007-03-27, released 2007-04-24
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.205
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DTDP-6-deoxy-3,4-keto-hexulose isomerase
    Species: Aneurinibacillus thermoaerophilus [TaxId:143495]
    Gene: fdtA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6T1W8
      • engineered (50)
      • engineered (52)
    Domains in SCOPe 2.02: d2pama1
  • Chain 'B':
    Compound: DTDP-6-deoxy-3,4-keto-hexulose isomerase
    Species: Aneurinibacillus thermoaerophilus [TaxId:143495]
    Gene: fdtA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6T1W8
      • engineered (50)
      • engineered (52)
    Domains in SCOPe 2.02: d2pamb_
  • Heterogens: TYD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pamA (A:)
ghmenkvinfkkiidsrgslvaieenknipfsikrvyyifdtkgeeprgfnankkleqvl
vclngscrvilddgniiqeitldspavglyvgpavwhemhdfssdcvmmvlasdyydetd
yirqydnfkkyiakinlekeg

    Sequence, based on observed residues (ATOM records): (download) 
    >2pamA (A:)
enkvinfkkiidsrgslvaieenknipfsikrvyyifdtkgeeprgfnankkleqvlvcl
ngscrvilddgniiqeitldspavglyvgpavwhemhdfssdcvmmvlasdyydetdyir
qydnfkkyiakinle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pamB (B:)
ghmenkvinfkkiidsrgslvaieenknipfsikrvyyifdtkgeeprgfnankkleqvl
vclngscrvilddgniiqeitldspavglyvgpavwhemhdfssdcvmmvlasdyydetd
yirqydnfkkyiakinlekeg

    Sequence, based on observed residues (ATOM records): (download) 
    >2pamB (B:)
enkvinfkkiidsrgslvaieenknipfsikrvyyifdtkgeeprgfnankkleqvlvcl
ngscrvilddgniiqeitldspavglyvgpavwhemhdfssdcvmmvlasdyydetdyir
qydnfkkyiakinl