PDB entry 2p9g

View 2p9g on RCSB PDB site
Description: Crystal structure of serine bound G336V,G337V double mutant of E.coli phosphoglycerate dehydrogenase
Class: oxidoreductase
Keywords: oxidoreductase, serine biosynthesis, D-3-phosphoglycerate dehydrogenase, double mutation
Deposited on 2007-03-25, released 2007-04-24
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: D-3-phosphoglycerate dehydrogenase
    Species: Escherichia coli [TaxId:562]
    Gene: serA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A9T0 (Start-409)
      • engineered (80)
      • engineered (82)
      • engineered (249)
      • engineered (281)
      • engineered (335-336)
    Domains in SCOPe 2.07: d2p9ga1, d2p9ga2, d2p9ga3
  • Chain 'B':
    Compound: D-3-phosphoglycerate dehydrogenase
    Species: Escherichia coli [TaxId:562]
    Gene: serA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A9T0 (Start-409)
      • engineered (80)
      • engineered (82)
      • engineered (249)
      • engineered (281)
      • engineered (335-336)
    Domains in SCOPe 2.07: d2p9gb1, d2p9gb2, d2p9gb3
  • Heterogens: NAI, SER, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2p9gA (A:)
makvslekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglr
srthltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigel
llllrgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfy
dienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasr
gtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqea
qeniglevagklikysdngstlsavnfpevslplhvvrrlmhihenrpgvltalnkifae
qgvniaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

    Sequence, based on observed residues (ATOM records): (download) 
    >2p9gA (A:)
ekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglrsrthlt
edvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigelllllrg
vpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfydienkl
plgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasrgtvvdi
paladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqeaqenigl
evagklikysdngstlsavnfpevslplhvvrrlmhihenrpgvltalnkifaeqgvnia
aqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2p9gB (B:)
makvslekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglr
srthltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigel
llllrgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfy
dienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasr
gtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqea
qeniglevagklikysdngstlsavnfpevslplhvvrrlmhihenrpgvltalnkifae
qgvniaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

    Sequence, based on observed residues (ATOM records): (download) 
    >2p9gB (B:)
ekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglrsrthlt
edvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigelllllrg
vpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfydienkl
plgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasrgtvvdi
paladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqeaqenigl
evagklikysdngstlsavnfpevslplhvvrrlmhihenrpgvltalnkifaeqgvnia
aqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly