SCOP 1.73: Structural Classification of Proteins

PDB entry 2p9e

View 2p9e on RCSB PDB site
Description: Crystal Structure of G336V mutant of E.coli phosphoglycerate dehydrogenase
Class: oxidoreductase
Keywords: oxidoreductase, G336V mutant, phosphoglycerate dehydrogenase, serine biosynthesis
Deposited on 2007-03-25, released 2007-04-24
The last revision prior to the SCOP 1.73 freeze date was dated 2007-07-17, with a file datestamp of 2007-07-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.21
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: D-3-phosphoglycerate dehydrogenase
Species: Escherichia coli
Gene: serA
Database cross-references and differences (RAF-indexed):
- Uniprot P0A9T0 (Start-409)
  - engineered (80)
  - engineered (82)
  - engineered (249)
  - engineered (281)
  - engineered (335)
Domains in SCOP 1.73: d2p9ea1, d2p9ea2, d2p9ea3
Chain 'B':
Compound: D-3-phosphoglycerate dehydrogenase
Species: Escherichia coli
Gene: serA
Database cross-references and differences (RAF-indexed):
- Uniprot P0A9T0 (Start-409)
  - engineered (80)
  - engineered (82)
  - engineered (249)
  - engineered (281)
  - engineered (335)
Domains in SCOP 1.73: d2p9eb1, d2p9eb2, d2p9eb3
Chain 'C':
Compound: D-3-phosphoglycerate dehydrogenase
Species: Escherichia coli
Gene: serA
Database cross-references and differences (RAF-indexed):
- Uniprot P0A9T0 (Start-409)
  - engineered (80)
  - engineered (82)
  - engineered (249)
  - engineered (281)
  - engineered (335)
Domains in SCOP 1.73: d2p9ec1, d2p9ec2, d2p9ec3
Chain 'D':
Compound: D-3-phosphoglycerate dehydrogenase
Species: Escherichia coli
Gene: serA
Database cross-references and differences (RAF-indexed):
- Uniprot P0A9T0 (Start-409)
  - engineered (80)
  - engineered (82)
  - engineered (249)
  - engineered (281)
  - engineered (335)
Domains in SCOP 1.73: d2p9ed1, d2p9ed2, d2p9ed3
Heterogens: PO4, SO4, NAI, CIT, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2p9eA (A:)
makvslekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglr
srthltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigel
llllrgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfy
dienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasr
gtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqea
qeniglevagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifae
qgvniaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Sequence, based on observed residues (ATOM records): (download)

>2p9eA (A:)
slekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglrsrth
ltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigelllll
rgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfydien
klplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasrgtvv
dipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqeaqeni
glevagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifaeqgvn
iaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Chain 'B':
Sequence, based on SEQRES records: (download)

>2p9eB (B:)
makvslekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglr
srthltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigel
llllrgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfy
dienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasr
gtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqea
qeniglevagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifae
qgvniaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Sequence, based on observed residues (ATOM records): (download)

>2p9eB (B:)
ekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglrsrthlt
edvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigelllllrg
vpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfydienkl
plgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasrgtvvdi
paladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqeaqenigl
evagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifaeqgvnia
aqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Chain 'C':
Sequence, based on SEQRES records: (download)

>2p9eC (C:)
makvslekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglr
srthltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigel
llllrgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfy
dienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasr
gtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqea
qeniglevagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifae
qgvniaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Sequence, based on observed residues (ATOM records): (download)

>2p9eC (C:)
slekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglrsrth
ltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigelllll
rgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfydien
klplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasrgtvv
dipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqeaqeni
glevagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifaeqgvn
iaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Chain 'D':
Sequence, based on SEQRES records: (download)

>2p9eD (D:)
makvslekdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglr
srthltedvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigel
llllrgvpeanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfy
dienklplgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasr
gtvvdipaladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqea
qeniglevagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifae
qgvniaaqylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly

Sequence, based on observed residues (ATOM records): (download)

>2p9eD (D:)
kdkikfllvegvhqkaleslraagytniefhkgalddeqlkesirdahfiglrsrthlte
dvinaaeklvaigafaigtnqvdldaaakrgipvfnapfsntrsvaelvigelllllrgv
peanakahrgvwnklaagsfeargkklgiigyghigtqlgilaeslgmyvyfydienklp
lgnatqvqhlsdllnmsdvvslhvpenpstknmmgakeislmkpgsllinasrgtvvdip
aladalaskhlagaaidvfptepatnsdpftsplaefdnvlltphiggstqeaqenigle
vagklikysdngstlsavnfpevslplhvgrrlmhihenrpgvltalnkifaeqgvniaa
qylqtsaqmgyvvidieadedvaekalqamkaipgtirarlly