PDB entry 2p5n

View 2p5n on RCSB PDB site
Description: Crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase in complex with coenzyme NADPH
Class: oxidoreductase
Keywords: Aldo-keto reductase, Hydroxysteroid Dehydrogenase, Binary Complex, TIM barrel, OXIDOREDUCTASE
Deposited on 2007-03-15, released 2007-10-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-11-20, with a file datestamp of 2013-11-15.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.201
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1, member C21
    Species: Mus musculus [TaxId:10090]
    Gene: Akr1c21
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6P8V0 (0-322)
      • see remark 999 (293)
    Domains in SCOPe 2.08: d2p5na_
  • Chain 'B':
    Compound: Aldo-keto reductase family 1, member C21
    Species: Mus musculus [TaxId:10090]
    Gene: Akr1c21
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6P8V0 (0-322)
      • see remark 999 (293)
    Domains in SCOPe 2.08: d2p5nb_
  • Heterogens: NDP, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2p5nA (A:)
mnskchcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedh
vgeairskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypm
alkpgeenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkp
glkykpvcnqvechpylnqmklldfckskdivlvaygvlgtqryggwvdqnspvlldepv
lgsmakkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldgln
rnmryipaaifkghpnwpfldey

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2p5nB (B:)
mnskchcvilndgnfipvlgfgtalplecpkskakeltkiaidagfhhfdsasvyntedh
vgeairskiadgtvrredifytskvwctslhpelvraslerslqklqfdyvdlylihypm
alkpgeenfpvdehgklifdrvdlcatweamekckdagltksigvsnfnyrqlemilnkp
glkykpvcnqvechpylnqmklldfckskdivlvaygvlgtqryggwvdqnspvlldepv
lgsmakkynrtpalialryqlqrgivvlntslkeerikenmqvfefqlssedmkvldgln
rnmryipaaifkghpnwpfldey