PDB entry 2p42

View 2p42 on RCSB PDB site
Description: Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE3-mono-2 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold
Class: hydrolase/immune system
Keywords: semet phasing, camelid single-domain antibody, vhh, cab-rn05, RNAse a, yeast surface display., hydrolase-immune system complex
Deposited on 2007-03-11, released 2008-03-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.173
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2p42a_
  • Chain 'B':
    Compound: antibody cab-rn05
    Species: Camelus dromedarius [TaxId:9838]
    Database cross-references and differences (RAF-indexed):
    • PDB 2P42 (Start-122)
    Domains in SCOPe 2.07: d2p42b_
  • Chain 'C':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2p42c_
  • Chain 'D':
    Compound: antibody cab-rn05
    Species: Camelus dromedarius [TaxId:9838]
    Database cross-references and differences (RAF-indexed):
    • PDB 2P42 (Start-122)
    Domains in SCOPe 2.07: d2p42d_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2p42A (A:)
ketaaakferqhmdsstsaasssnycnqmmksrnltkdrckpvntfvhesladvqavcsq
knvackngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhf
dasv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2p42B (B:)
gsqvqlvesggglvqaggslrlscaasgyaytyiymgwfrqapgkeregvaamdsggggt
lyadsvkgrftisrdkgkntvylqmdslkpedtatyycaaggyelrdrtygqwgqgtqvt
vss

    Sequence, based on observed residues (ATOM records): (download) 
    >2p42B (B:)
qvqlvesggglvqaggslrlscaasgyaytyiymgwfrqapgkeregvaamdsggggtly
adsvkgrftisrdkgkntvylqmdslkpedtatyycaaggyelrdrtygqwgqgtqvtvs
s

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2p42C (C:)
ketaaakferqhmdsstsaasssnycnqmmksrnltkdrckpvntfvhesladvqavcsq
knvackngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhf
dasv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2p42D (D:)
gsqvqlvesggglvqaggslrlscaasgyaytyiymgwfrqapgkeregvaamdsggggt
lyadsvkgrftisrdkgkntvylqmdslkpedtatyycaaggyelrdrtygqwgqgtqvt
vss

    Sequence, based on observed residues (ATOM records): (download) 
    >2p42D (D:)
qvqlvesggglvqaggslrlscaasgyaytyiymgwfrqapgkeregvaamdsggggtly
adsvkgrftisrdkgkntvylqmdslkpedtatyycaaggyelrdrtygqwgqgtqvtvs
s