PDB entry 2p3u
View 2p3u on RCSB PDB site
Description: Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}
Class: blood clotting
Keywords: protein inhibitor complex, coagulation cofactor, protease, BLOOD CLOTTING
Deposited on
2007-03-09, released
2007-09-11
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: 0.192
AEROSPACI score: 0.58
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: coagulation factor x
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2p3ua_ - Chain 'B':
Compound: coagulation factor x
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2p3ub_ - Heterogens: CA, 663, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2p3uA (A:)
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle
Sequence, based on observed residues (ATOM records): (download)
>2p3uA (A:)
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtl
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2p3uB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk