PDB entry 2p3t
View 2p3t on RCSB PDB site
Description: Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide
Class: blood clotting
Keywords: protein inhibitor complex, nonamidine, coagulation cofactor, protease, BLOOD CLOTTING
Deposited on
2007-03-09, released
2008-01-22
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: 0.192
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: coagulation factor x
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d2p3ta_ - Chain 'B':
Compound: coagulation factor x
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d2p3tb_ - Heterogens: CA, CL, 993, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2p3tA (A:)
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2p3tB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
Sequence, based on observed residues (ATOM records): (download)
>2p3tB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qegeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtq
ktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacq
gdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk