PDB entry 2p3t

View 2p3t on RCSB PDB site
Description: Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide
Class: blood clotting
Keywords: protein inhibitor complex, nonamidine, coagulation cofactor, protease, BLOOD CLOTTING
Deposited on 2007-03-09, released 2008-01-22
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: 0.192
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: coagulation factor x
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2p3ta_
  • Chain 'B':
    Compound: coagulation factor x
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2p3tb_
  • Heterogens: CA, CL, 993, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2p3tA (A:)
    klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2p3tB (B:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2p3tB (B:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qegeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtq
    ktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacq
    gdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk