PDB entry 2p1v

View 2p1v on RCSB PDB site
Description: Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-propoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2
Class: hormone receptor
Keywords: protein-ligand complex, HORMONE RECEPTOR
Deposited on 2007-03-06, released 2007-10-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.198
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2p1va_
  • Chain 'B':
    Compound: Nuclear receptor coactivator 2 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 5TN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2p1vA (A:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >2p1vA (A:)
dmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillragwne
lliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktel
gclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrs
iglkclehlfffkligdtpidtflmemleap

  • Chain 'B':
    No sequence available.