PDB entry 2p1t
View 2p1t on RCSB PDB site
Description: Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-methoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2
Class: hormone receptor
Keywords: protein-ligand complex, HORMONE RECEPTOR
Deposited on
2007-03-06, released
2007-10-09
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.198
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Retinoic acid receptor RXR-alpha
Species: Homo sapiens [TaxId:9606]
Gene: RXRA, NR2B1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d2p1ta_ - Chain 'B':
Compound: Nuclear receptor coactivator 2 peptide
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: 3TN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2p1tA (A:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt
Sequence, based on observed residues (ATOM records): (download)
>2p1tA (A:)
dmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillragwne
lliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktel
gclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrs
iglkclehlfffkligdtpidtflmemleap
- Chain 'B':
No sequence available.