PDB entry 2p02

View 2p02 on RCSB PDB site
Description: Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2
Class: transferase
Keywords: SYNTHETASE, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2007-02-28, released 2007-03-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.21 Å
R-factor: 0.101
AEROSPACI score: 0.89 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthetase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2p02a1, d2p02a2, d2p02a3
  • Heterogens: CL, SAM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2p02A (A:)
    smngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetv
    aktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaq
    gvhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpd
    sktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakylded
    tiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaar
    wvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgv
    ivrdldlkkpiyqrtaayghfgrdsfpwevpkklky
    

    Sequence, based on observed residues (ATOM records): (download)
    >2p02A (A:)
    gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
    avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqgvhldrneedigagdq
    glmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgav
    lpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggp
    qgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvl
    vqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrta
    ayghfgrdsfpwevpkklky