PDB entry 2oz7

View 2oz7 on RCSB PDB site
Description: Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with cyproterone acetate
Class: hormone receptor
Keywords: androgen receptor, anti-androgen, prostate cancer, HORMONE RECEPTOR
Deposited on 2007-02-25, released 2007-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-03-09, with a file datestamp of 2011-03-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.253
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Androgen receptor
  Species: Homo sapiens [TaxId:9606]
  Gene: AR, DHTR, NR3C4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P10275 (0-248)
    • engineered (206)
  Domains in SCOPe 2.08: d2oz7a_
• Heterogens: CA4, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2oz7A (A:)
  piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
  ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
  sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
  scsrrfyqltklldsvqpiarelhqfafdllikshmvsvdfpemmaeiisvqvpkilsgk
  vkpiyfhtq