PDB entry 2oz5

View 2oz5 on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS
Class: structural genomics, unknown function
Keywords: Protein tyrosine phosphatase in complex with small molecule inhibitor, Structural Genomics, TB Structural Genomics Consortium, TBSGC, UNKNOWN FUNCTION
Deposited on 2007-02-23, released 2007-05-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.192
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphotyrosine protein phosphatase ptpb
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: ptpB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2oz5a_
  • Chain 'B':
    Compound: phosphotyrosine protein phosphatase ptpb
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: ptpB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2oz5b_
  • Heterogens: 7XY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2oz5A (A:)
mgsshhhhhhssglvprgshmavrelpgawnfrdvadtatalrpgrlfrsselsrlddag
ratlrrlgitdvadlrssrevarrgpgrvpdgidvhllpfpdladddaddsaphetafkr
lltndgsngesgessqsindaatrymtdeyrqfptrngaqralhrvvtllaagrpvlthc
fagkdrtgfvvalvleavgldrdvivadylrsndsvpqlrarisemiqqrfdtelapevv
tftkarlsdgvlgvraeylaaarqtidetygslggylrdagisqatvnrmrgvllg

    Sequence, based on observed residues (ATOM records): (download) 
    >2oz5A (A:)
relpgawnfrdvadtatalrpgrlfrsselsrlddagratlrrlgitdvadlrssrevar
rgpgrvpdgidvhllpfpdladdaddsaphetafkrlltngessqsindaatrymtdeyr
qfptrngaqralhrvvtllaagrpvlthcfagkdrtgfvvalvleavgldrdvivadylr
sndsvpqlrarisemiqqrfdtelapevvtftkarlsdgvlgvraeylaaarqtidetyg
slggylrdagisqatvnrmrgvllg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2oz5B (B:)
mgsshhhhhhssglvprgshmavrelpgawnfrdvadtatalrpgrlfrsselsrlddag
ratlrrlgitdvadlrssrevarrgpgrvpdgidvhllpfpdladddaddsaphetafkr
lltndgsngesgessqsindaatrymtdeyrqfptrngaqralhrvvtllaagrpvlthc
fagkdrtgfvvalvleavgldrdvivadylrsndsvpqlrarisemiqqrfdtelapevv
tftkarlsdgvlgvraeylaaarqtidetygslggylrdagisqatvnrmrgvllg

    Sequence, based on observed residues (ATOM records): (download) 
    >2oz5B (B:)
relpgawnfrdvadtatalrpgrlfrsselsrlddagratlrrlgitdvadlrssrevar
rgpgrvpdgidvhllpfpdladddaddsaphetafkrlltnsindaatrymtdeyrqfpt
rngaqralhrvvtllaagrpvlthcfagkdrtgfvvalvleavgldrdvivadylrsnds
vpqlrarisemiqqrfdtelapevvtftkarlsdgvlgvraeylaaarqtidetygslgg
ylrdagisqatvnrmrgvllg