PDB entry 2oxu

View 2oxu on RCSB PDB site
Description: Uninhibited form of human MMP-12
Class: hydrolase
Keywords: MMP-12, Matrix Metalloproteinase
Deposited on 2007-02-21, released 2007-03-06
The last revision prior to the SCOP 1.75 freeze date was dated 2007-03-06, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.24 Å
R-factor: 0.198
AEROSPACI score: 0.89 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Macrophage metalloelastase
    Species: HOMO SAPIENS
    Gene: MMP12, HME
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39900 (1-158)
      • engineered (66)
    Domains in SCOP 1.75: d2oxua1
  • Heterogens: ZN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2oxuA (A:)
mgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvfa
rgahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighsl
glghssdpkavmfptykyvdintfrlsaddirgiqslyg

    Sequence, based on observed residues (ATOM records): (download) 
    >2oxuA (A:)
gpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvfar
gahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighslg
lghssdpkavmfptykyvdintfrlsaddirgiqslyg