PDB entry 2owb

View 2owb on RCSB PDB site
Description: Structure of the Catalytic Domain of Human Polo-like Kinase 1
Class: transferase
Keywords: Catalytic domain, plk1, polo-like kinase1, kinase, TRANSFERASE
Deposited on 2007-02-15, released 2007-04-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.205
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P53350
      • engineered (199)
    Domains in SCOPe 2.06: d2owba_
  • Heterogens: ZN, ACT, 626, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2owbA (A:)
gpapadpgkagvpgvaapgapaaappakeipevlvdprsrrryvrgrflgkggfakcfei
sdadtkevfagkivpkslllkphqrekmsmeisihrslahqhvvgfhgffedndfvfvvl
elcrrrsllelhkrrkaltepearyylrqivlgcqylhrnrvihrdlklgnlflnedlev
kigdfglatkveydgerkkvlcgtpnyiapevlskkghsfevdvwsigcimytllvgkpp
fetsclketylrikkneysipkhinpvaasliqkmlqtdptarptinellndefftsgyi
parlpitcltipprfsiapssldpsnrkpltvlnk

    Sequence, based on observed residues (ATOM records): (download) 
    >2owbA (A:)
akeipevlvdprsrrryvrgrflgkggfakcfeisdadtkevfagkivpkslllkphqre
kmsmeisihrslahqhvvgfhgffedndfvfvvlelcrrrsllelhkrrkaltepearyy
lrqivlgcqylhrnrvihrdlklgnlflnedlevkigdfglatkveydgerkkvlcgtpn
yiapevlskkghsfevdvwsigcimytllvgkppfetsclketylrikkneysipkhinp
vaasliqkmlqtdptarptinellndefftsgyiparlpitcltipprfsiaps