PDB entry 2ovz
View 2ovz on RCSB PDB site
Description: MMP-9 active site mutant with phosphinate inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: MATRIX METALLOPROTEINASE, S1-PRIME POCKET, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2007-02-15, released
2007-06-19
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.221
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Matrix metalloproteinase-9 (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB)
Species: Homo sapiens [TaxId:9606]
Gene: MMP9, CLG4B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2ovza_ - Chain 'B':
Compound: Matrix metalloproteinase-9 (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB)
Species: Homo sapiens [TaxId:9606]
Gene: MMP9, CLG4B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2ovzb_ - Heterogens: ZN, CA, CL, 5MR, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2ovzA (A:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
halgldhssvpealmypmyrftegpplhkddvngirhly
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2ovzB (B:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
halgldhssvpealmypmyrftegpplhkddvngirhly
Sequence, based on observed residues (ATOM records): (download)
>2ovzB (B:)
lkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviqfgva
ehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfghalg
ldhssvpealmypmyrftegpplhkddvngirhly