PDB entry 2ovr

View 2ovr on RCSB PDB site
Description: Structure of the Skp1-Fbw7-CyclinEdegN complex
Class: transcription/cell cycle
Keywords: F-box; WD40 domains; double phosphorylation
Deposited on 2007-02-14, released 2007-04-24
The last revision prior to the SCOP 1.73 freeze date was dated 2007-04-24, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.225
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: S-phase kinase-associated protein 1A
  Species: HOMO SAPIENS
  Gene: SKP1A, EMC19, OCP2, SKP1, TCEB1L
  Database cross-references and differences (RAF-indexed):
  • Uniprot P63208 (Start-134)
  Domains in SCOP 1.73: d2ovra1, d2ovra2
• Chain 'B':
  Compound: F-box/WD repeat protein 7
  Species: HOMO SAPIENS
  Gene: FBXW7, FBW7, FBX30, SEL10
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q969H0 (0-End)
• Chain 'C':
  Compound: cyclinE N-terminal degron
  Species: synthetic, synthetic
  
• Heterogens: SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >2ovrA (A:)
  mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
  ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
  irktfnikndfteeeeaqvrkenqwceek
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >2ovrA (A:)
  psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhdd
  ipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfniknd
  fteeeeaqvrkenqwc
  

  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.