PDB entry 2opm

View 2opm on RCSB PDB site
Description: Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461
Class: transferase
Keywords: protein-bisphosphonate complex, transferase
Deposited on 2007-01-29, released 2007-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.234
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)]
    Species: Homo sapiens [TaxId:9606]
    Gene: FDPS, FPS, KIAA1293
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2opma_
  • Heterogens: PO4, MG, NI9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2opmA (A:)
gsshhhhhhssgrenlyfqghmngdqnsdvyaqekqdfvqhfsqivrvltedemghpeig
daiarlkevleynaiggkynrgltvvvafrelveprkqdadslqrawtvgwcvellqaff
lvaddimdssltrrgqicwyqkpgvgldaindanlleaciyrllklycreqpyylnliel
flqssyqteigqtldlltapqgnvdlvrftekryksivkyktafysfylpiaaamymagi
dgekehanakkillemgeffqiqddyldlfgdpsvtgkigtdiqdnkcswlvvqclqrat
peqyqilkenygqkeaekvarvkalyeeldlpavflqyeedsyshimalieqyaaplppa
vflglarkiykrrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2opmA (A:)
ekqdfvqhfsqivrvltedehpeigdaiarlkevleynaiggkynrgltvvvafrelvep
rkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldaindanl
leaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrftekryk
sivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdpsv
tgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlpavf
lqyeedsyshimalieqyaaplppavflglarkiyk