PDB entry 2oju

View 2oju on RCSB PDB site
Description: X-ray structure of complex of human cyclophilin J with cyclosporin A
Class: isomerase/immunosuppressant
Keywords: isomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin a, immunosuppressant, cyclophilin
Deposited on 2007-01-14, released 2008-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-27, with a file datestamp of 2011-07-22.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.193
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase-like 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PPIL3b
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H2H8 (6-End)
      • expression tag (2-5)
    Domains in SCOPe 2.08: d2ojua2, d2ojua3
  • Chain 'B':
    Compound: Peptidyl-prolyl cis-trans isomerase-like 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PPIL3b
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H2H8 (6-End)
      • expression tag (0-5)
    Domains in SCOPe 2.08: d2ojub2, d2ojub3
  • Chain 'C':
    Compound: cyclosporin a
    Species: Tolypocladium inflatum, synthetic [TaxId:29910]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00033 (0-10)
  • Chain 'D':
    Compound: cyclosporin a
    Species: Tolypocladium inflatum, synthetic [TaxId:29910]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00033 (0-10)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ojuA (A:)
srvdggmsvtlhtdvgdikievfcertpktcenflalcasnyyngcifhrnikgfmvqtg
dptgtgrggnsiwgkkfedeyseylkhnvrgvvsmanngpntngsqffitygkqphldmk
ytvfgkvidgletldeleklpvnektyrplndvhikditihanpfaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ojuA (A:)
vdggmsvtlhtdvgdikievfcertpktcenflalcasnyyngcifhrnikgfmvqtgdp
tgtgrggnsiwgkkfedeyseylkhnvrgvvsmanngpntngsqffitygkqphldmkyt
vfgkvidgletldeleklpvnektyrplndvhikditihanpf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ojuB (B:)
srvdggmsvtlhtdvgdikievfcertpktcenflalcasnyyngcifhrnikgfmvqtg
dptgtgrggnsiwgkkfedeyseylkhnvrgvvsmanngpntngsqffitygkqphldmk
ytvfgkvidgletldeleklpvnektyrplndvhikditihanpfaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ojuB (B:)
srvdggmsvtlhtdvgdikievfcertpktcenflalcasnyyngcifhrnikgfmvqtg
dptgtgrggnsiwgkkfedeyseylkhnvrgvvsmanngpntngsqffitygkqphldmk
ytvfgkvidgletldeleklpvnektyrplndvhikditihanpfa

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.