PDB entry 2oji
View 2oji on RCSB PDB site
Description: Crystal structure of ERK2 in complex with N-benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Class: transferase
Keywords: kinase inhibitor, TRANSFERASE
Deposited on
2007-01-12, released
2007-02-06
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.215
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Mitogen-activated protein kinase 1
Species: Homo sapiens [TaxId:9606]
Gene: MAPK1, ERK2, PRKM1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d2ojia_ - Heterogens: SO4, 33A, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2ojiA (A:)
mgsshhhhhhssglvprgshmaaaaaagagpemvrgqvfdvgprytnlsyigegaygmvc
saydnvnkvrvaikkispfehqtycqrtlreikillrfrheniigindiiraptieqmkd
vyivqdlmetdlykllktqhlsndhicyflyqilrglkyihsanvlhrdlkpsnlllntt
cdlkicdfglarvadpdhdhtgflteyvatrwyrapeimlnskgytksidiwsvgcilae
mlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnyllslphknkvpwnrlfp
nadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiaeapfkfdmelddlpk
eklkelifeetarfqpgyrs
Sequence, based on observed residues (ATOM records): (download)
>2ojiA (A:)
rgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlreiki
llrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyflyqil
rglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrwyr
apeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnc
iinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyle
qyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy