PDB entry 2ojg

View 2ojg on RCSB PDB site
Description: Crystal structure of ERK2 in complex with N,N-dimethyl-4-(4-phenyl-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Class: transferase
Keywords: kinase inhibitor, TRANSFERASE
Deposited on 2007-01-12, released 2007-02-06
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.22
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK1, ERK2, PRKM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ojga_
  • Heterogens: SO4, 19A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ojgA (A:)
    mgsshhhhhhssglvprgshmaaaaaagagpemvrgqvfdvgprytnlsyigegaygmvc
    saydnvnkvrvaikkispfehqtycqrtlreikillrfrheniigindiiraptieqmkd
    vyivqdlmetdlykllktqhlsndhicyflyqilrglkyihsanvlhrdlkpsnlllntt
    cdlkicdfglarvadpdhdhtgflteyvatrwyrapeimlnskgytksidiwsvgcilae
    mlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnyllslphknkvpwnrlfp
    nadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiaeapfkfdmelddlpk
    eklkelifeetarfqpgyrs
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ojgA (A:)
    fdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtlreikillrf
    rheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyflyqilrglk
    yihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrwyrapei
    mlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinl
    karnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyyd
    psdepiaeapfkfelddlpkeklkelifeetarfqpg