PDB entry 2oib

View 2oib on RCSB PDB site
Description: Crystal structure of IRAK4 kinase domain apo form
Class: Transferase
Keywords: KINASE, HELIC C, Transferase
Deposited on 2007-01-10, released 2007-03-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.224
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (182)
      • modified residue (185-186)
    Domains in SCOPe 2.08: d2oiba_
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (185-186)
    Domains in SCOPe 2.08: d2oibb_
  • Chain 'C':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (182)
      • modified residue (185-186)
    Domains in SCOPe 2.08: d2oibc_
  • Chain 'D':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NWZ3
      • modified residue (182)
      • modified residue (185-186)
    Domains in SCOPe 2.08: d2oibd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2oibA (A:)
vsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamv
ditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldg
tpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekf
aqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldi
keeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2oibA (A:)
dtrfhsfsfyelknvtnnfderpisvggnkmgegvvykgyvnnttvavkktteelkqqfd
qeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrcki
aqgaanginflhenhhihrdiksanilldeaftakisdfglarasetvmtsrivgttaym
apealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyid
kkmndadstsveamysvasqclhekknkrpdikkvqqllqemt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2oibB (B:)
vsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamv
ditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldg
tpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekf
aqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldi
keeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2oibB (B:)
rfhsfsfyelknvtnnfderpisgnkmgegvvykgyvnnttvavkklateelkqqfdqei
kvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckiaqg
aanginflhenhhihrdiksanilldeaftakisdfglarasevmtsrivgttaymapea
lrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmn
dadstsveamysvasqclhekknkrpdikkvqqllqemta

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2oibC (C:)
vsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamv
ditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldg
tpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekf
aqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldi
keeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2oibC (C:)
sdtrfhsfsfyelknvtnnfderpiskmggfgvvykgyvnnttvavkklaeelkqqfdqe
ikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckiaq
gaanginflhenhhihrdiksanilldeaftakisdfglaraaqtvmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2oibD (D:)
vsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamv
ditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldg
tpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekf
aqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldi
keeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2oibD (D:)
dtrfhsfsfyelknvtnnfderpisvgnkmgeggfgvvykgyvnnttvavkkltteelkq
qfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmr
ckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtvmtsri
vgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeek
tiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta