PDB entry 2oh4

View 2oh4 on RCSB PDB site
Description: Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor
Class: transferase
Keywords: Vascular endothelial growth factor receptor 2, Tyrosine-protein kinase, Angiogenesis, ATP-binding, Phosphorylation, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, Transferase
Deposited on 2007-01-09, released 2007-09-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vascular endothelial growth factor receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: KDR, FLK1, VEGFR2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2oh4a1, d2oh4a2
  • Heterogens: SO4, GIG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2oh4A (A:)
hmdpdelpldehcerlpydaskwefprdrlnlgkplgrgafgqvieadafgidktatcrt
vavkmlkegathsehralmselkilihighhlnvvnllgactkpggplmvivefckfgnl
stylrskrnefvpyktpedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnil
lseknvvkicdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvll
weifslgaspypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfse
lvehlgnllqanaqqd

    Sequence, based on observed residues (ATOM records): (download) 
    >2oh4A (A:)
hcerlpydaskwefprdrlnlgkplgrgafgqvieadafgidktatcrtvavkmlkegat
hsehralmselkilihighhlnvvnllgactkpggplmvivefckfgnlstylrskrnef
vpyykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdfglard
iykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweifslgaspypgvkid
eefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselvehlgnllqanaqqd