PDB entry 2o8w
View 2o8w on RCSB PDB site
Description: Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors
Class: hydrolase
Keywords: urokinase-type plasminogen activator, benzamidine, phenylguanidine, contact area, HYDROLASE
Deposited on
2006-12-12, released
2007-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.213
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Urokinase plasminogen activator
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5PY49 (0-End)
- engineered (120)
- engineered (143)
- engineered (197)
Domains in SCOPe 2.08: d2o8wa_ - Heterogens: SO4, PG4, PL0, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2o8wA (A:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdaggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkeenglal
Sequence, based on observed residues (ATOM records): (download)
>2o8wA (A:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
alpsmyndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdaggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irsht