PDB entry 2o5z

View 2o5z on RCSB PDB site
Description: Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab 5-beta-androstane-3,17-dione complex
Class: immune system
Keywords: immunoglobulin, chimeric Fab, antibody engineering, evolution of ligand recognition, IMMUNE SYSTEM
Deposited on 2006-12-06, released 2007-12-18
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.174
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: chimeric antibody Fab 1E9-DB3
    Species: Mus musculus, Homo sapiens [TaxId:10090,9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2O5Z (0-End)
  • Chain 'L':
    Compound: chimeric antibody Fab 1E9-DB3
    Species: Mus musculus, Homo sapiens [TaxId:10090,9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2O5Z (0-End)
    Domains in SCOPe 2.03: d2o5zl1, d2o5zl2
  • Heterogens: SO4, ANO, HOH

PDB Chain Sequences:

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2o5zL (L:)
elvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspkfliykvsnrf
sgvpdrfsgsgsgtdfilkisrveaedlgvyfcfqsthffptfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >2o5zL (L:)
elvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspkfliykvsnrf
sgvpdrfsgsgsgtdfilkisrveaedlgvyfcfqsthffptfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge