PDB entry 2o4p

View 2o4p on RCSB PDB site
Description: Crystal Structure of HIV-1 Protease (Q7K) in Complex with Tipranavir
Class: Viral Protein
Keywords: protease
Deposited on 2006-12-04, released 2006-12-12
The last revision prior to the SCOP 1.75 freeze date was dated 2007-08-21, with a file datestamp of 2007-08-17.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.203
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gag-Pol polyprotein (Pr160Gag-Pol)
    Species: Human immunodeficiency virus type 1
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (6)
    Domains in SCOP 1.75: d2o4pa1
  • Chain 'B':
    Compound: Gag-Pol polyprotein (Pr160Gag-Pol)
    Species: Human immunodeficiency virus type 1
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03367 (0-98)
      • engineered (6)
    Domains in SCOP 1.75: d2o4pb1
  • Heterogens: TPV, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2o4pA (A:)
    pqitlwkrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2o4pB (B:)
    pqitlwkrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf