PDB entry 2o3k

View 2o3k on RCSB PDB site
Description: Yeast Cytosine Deaminase D92E Triple Mutant bound to transition state analogue HPY
Class: hydrolase
Keywords: Homodimer, Transition State Analogue, HYDROLASE
Deposited on 2006-12-01, released 2007-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytosine deaminase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: fcy1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12178
      • engineered (25)
      • engineered (94)
      • engineered (110)
      • engineered (142)
    Domains in SCOPe 2.08: d2o3ka_
  • Chain 'B':
    Compound: Cytosine deaminase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: fcy1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12178 (Start-160)
      • engineered (25)
      • engineered (94)
      • engineered (110)
      • engineered (142)
    Domains in SCOPe 2.08: d2o3kb_
  • Heterogens: ZN, HPY, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2o3kA (A:)
gssmvtggmaskwdqkgmdiayeeallgykeggvpiggclinnkdgsvlgrghnmrfqkg
satlhgeistlencgrlegkvykdttlyttlspcemctgaiimygiprcvigenvnfksk
gekylqtrghevvvvdderckklmkqfiderpqdwfedige

    Sequence, based on observed residues (ATOM records): (download) 
    >2o3kA (A:)
gmaskwdqkgmdiayeeallgykeggvpiggclinnkdgsvlgrghnmrfqkgsatlhge
istlencgrlegkvykdttlyttlspcemctgaiimygiprcvigenvnfkskgekylqt
rghevvvvdderckklmkqfiderpqdwfedige

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2o3kB (B:)
gssmvtggmaskwdqkgmdiayeeallgykeggvpiggclinnkdgsvlgrghnmrfqkg
satlhgeistlencgrlegkvykdttlyttlspcemctgaiimygiprcvigenvnfksk
gekylqtrghevvvvdderckklmkqfiderpqdwfedige

    Sequence, based on observed residues (ATOM records): (download) 
    >2o3kB (B:)
maskwdqkgmdiayeeallgykeggvpiggclinnkdgsvlgrghnmrfqkgsatlhgei
stlencgrlegkvykdttlyttlspcemctgaiimygiprcvigenvnfkskgekylqtr
ghevvvvdderckklmkqfiderpqdwfedige