PDB entry 2o3h

View 2o3h on RCSB PDB site
Description: Crystal structure of the human C65A Ape
Class: lyase
Keywords: ape, endonuclease, lyase
Deposited on 2006-12-01, released 2007-12-11
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-06-16, with a file datestamp of 2009-06-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.177
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-(apurinic or apyrimidinic site) lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: APEX1, APE, APEX, APX, HAP1, REF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27695 (6-284)
      • expression tag (3-5)
      • engineered (31)
    Domains in SCOPe 2.04: d2o3ha_
  • Heterogens: SM, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2o3hA (A:)
gshmasegpalyedppdqktspsgkpatlkiaswnvdglrawikkkgldwvkeeapdilc
lqetkcsenklpaelqelpglshqywsapsdkegysgvgllsrqcplkvsygigdeehdq
egrvivaefdsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnv
aheeidlrnpkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmna
rsknvgwrldyfllshsllpalcdskirskalgsdhcpitlylal

    Sequence, based on observed residues (ATOM records): (download) 
    >2o3hA (A:)
masegpalyedppdqktspsgkpatlkiaswnvdglrawikkkgldwvkeeapdilclqe
tkcsenklpaelqelpglshqywsapsegysgvgllsrqcplkvsygigdeehdqegrvi
vaefdsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheei
dlrnpkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknv
gwrldyfllshsllpalcdskirskalgsdhcpitlylal