PDB entry 2o3b

View 2o3b on RCSB PDB site
Description: Crystal structure complex of Nuclease A (NucA) with intra-cellular inhibitor NuiA
Class: hydrolase/hydrolase inhibitor
Keywords: Nuclease, Nuclease inhibitor, Metal complex, non-specific nuclease, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2006-12-01, released 2006-12-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.201
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclease
    Species: Nostoc sp. [TaxId:103690]
    Gene: nucA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38446 (1-240)
      • cloning artifact (0)
      • engineered (87)
    Domains in SCOPe 2.08: d2o3ba1, d2o3ba2
  • Chain 'B':
    Compound: Sugar-non-specific nuclease inhibitor
    Species: Nostoc sp. [TaxId:103690]
    Gene: nuiA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7A260 (2-135)
      • cloning artifact (1)
    Domains in SCOPe 2.08: d2o3bb2, d2o3bb3
  • Heterogens: NI, MG, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2o3bA (A:)
gsisvhlllgnpsgatptkltpdnylmvknqyalsynnskgtanwvawqlnsswlgnaer
qdnfrpdktlpagwvrvtpsmysgsgyarghiapsadrtkttednaatflmtnmmpqtpd
nnrntwgnledycrelvsqgkelyivagpngslgkplkgkvtvpkstwkivvvldspgsg
legitantrviavnipndpelnndwraykvsvdelesltgydflsnvspniqtsieskvd
n

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2o3bB (B:)
gstktnseileqlkqasdgllfmseseypfevflwegsappvtheivlqqtghgqdapfk
vvdidsffsrattpqdwyedeenavvakfqklleviksnlknpqvyrlgeveldvyvige
tpagnlagistkvvet

    Sequence, based on observed residues (ATOM records): (download) 
    >2o3bB (B:)
stktnseileqlkqasdgllfmseseypfevflwegsappvtheivlqqtghgqdapfkv
vdidsffsrattpqdwyedeenavvakfqklleviksnlknpqvyrlgeveldvyviget
pagnlagistkvvet