PDB entry 2o25

View 2o25 on RCSB PDB site
Description: Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9
Class: ligase
Keywords: Ligase; Ubl conjugation pathway, Structural Genomics Consortium, SGC, LIGASE
Deposited on 2006-11-29, released 2007-01-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.231
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2-25 kDa
    Species: Homo sapiens [TaxId:9606]
    Gene: HIP2, LIG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2o25a1, d2o25a2
  • Chain 'B':
    Compound: Ubiquitin-conjugating enzyme E2-25 kDa
    Species: Homo sapiens [TaxId:9606]
    Gene: HIP2, LIG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2o25b1, d2o25b2
  • Chain 'C':
    Compound: SUMO-1-conjugating enzyme UBC9
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2I, UBC9, UBCE9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2o25c_
  • Chain 'D':
    Compound: SUMO-1-conjugating enzyme UBC9
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2I, UBC9, UBCE9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2o25d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2o25A (A:)
    gsmaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryql
    eikipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqalla
    aaepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrna
    vivalsskswdvetatelllsn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o25A (A:)
    maniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryqlei
    kipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqallaaa
    epddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrnavi
    valsskswdvetatellls
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2o25B (B:)
    gsmaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryql
    eikipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqalla
    aaepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrna
    vivalsskswdvetatelllsn
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o25B (B:)
    niavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryqleiki
    petypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqallaaaep
    ddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrnaviva
    lsskswdvetatellls
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2o25C (C:)
    gsmsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglf
    klrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqe
    llnepniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o25C (C:)
    sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklr
    mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
    epniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2o25D (D:)
    gsmsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglf
    klrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqe
    llnepniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

    Sequence, based on observed residues (ATOM records): (download)
    >2o25D (D:)
    sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklr
    mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
    epniqdpaqaeaytiycqnrveyekrvraqakkfap