PDB entry 2o25

View 2o25 on RCSB PDB site
Description: Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9
Class: ligase
Keywords: Ligase; Ubl conjugation pathway, Structural Genomics Consortium, SGC
Deposited on 2006-11-29, released 2007-01-16
The last revision prior to the SCOP 1.75 freeze date was dated 2007-03-27, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.231
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2-25 kDa
    Species: HOMO SAPIENS
    Gene: HIP2, LIG
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2o25a1, d2o25a2
  • Chain 'B':
    Compound: Ubiquitin-conjugating enzyme E2-25 kDa
    Species: HOMO SAPIENS
    Gene: HIP2, LIG
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2o25b1, d2o25b2
  • Chain 'C':
    Compound: SUMO-1-conjugating enzyme UBC9
    Species: HOMO SAPIENS
    Gene: UBE2I, UBC9, UBCE9
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2o25c1
  • Chain 'D':
    Compound: SUMO-1-conjugating enzyme UBC9
    Species: HOMO SAPIENS
    Gene: UBE2I, UBC9, UBCE9
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2o25d1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2o25A (A:)
gsmaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryql
eikipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqalla
aaepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrna
vivalsskswdvetatelllsn

    Sequence, based on observed residues (ATOM records): (download) 
    >2o25A (A:)
maniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryqlei
kipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqallaaa
epddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrnavi
valsskswdvetatellls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2o25B (B:)
gsmaniavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryql
eikipetypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqalla
aaepddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrna
vivalsskswdvetatelllsn

    Sequence, based on observed residues (ATOM records): (download) 
    >2o25B (B:)
niavqrikrefkevlkseetsknqikvdlvdenftelrgeiagppdtpyeggryqleiki
petypfnppkvrfitkiwhpnissvtgaicldilkdqwaaamtlrtvllslqallaaaep
ddpqdavvanqykqnpemfkqtarlwahvyagapvsspeytkkienlcamgfdrnaviva
lsskswdvetatellls

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2o25C (C:)
gsmsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglf
klrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqe
llnepniqdpaqaeaytiycqnrveyekrvraqakkfaps

    Sequence, based on observed residues (ATOM records): (download) 
    >2o25C (C:)
sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklr
mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
epniqdpaqaeaytiycqnrveyekrvraqakkfaps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2o25D (D:)
gsmsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglf
klrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqe
llnepniqdpaqaeaytiycqnrveyekrvraqakkfaps

    Sequence, based on observed residues (ATOM records): (download) 
    >2o25D (D:)
sgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklr
mlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqelln
epniqdpaqaeaytiycqnrveyekrvraqakkfap