PDB entry 2nz9

View 2nz9 on RCSB PDB site
Description: Crystal structure of botulinum neurotoxin type A complexed with monoclonal antibody AR2
Class: toxin/immune system
Keywords: botulinum, neurotoxin, fab, protein antibody complex, toxin-immune system complex
Deposited on 2006-11-22, released 2006-12-26
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-10-02, with a file datestamp of 2013-09-27.
Experiment type: XRAY
Resolution: 3.79 Å
R-factor: 0.227
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Botulinum neurotoxin type A
    Species: Clostridium botulinum [TaxId:1491]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: AR2 monoclonal antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NZ9 (0-End)
    Domains in SCOPe 2.05: d2nz9c1, d2nz9c2
  • Chain 'D':
    Compound: AR2 monoclonal antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NZ9
    Domains in SCOPe 2.05: d2nz9d1, d2nz9d2
  • Chain 'E':
    Compound: AR2 monoclonal antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NZ9 (0-End)
    Domains in SCOPe 2.05: d2nz9e1, d2nz9e2
  • Chain 'F':
    Compound: AR2 monoclonal antibody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2NZ9
    Domains in SCOPe 2.05: d2nz9f1, d2nz9f2
  • Heterogens: ZN, CA

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2nz9C (C:)
    eivltqspatlslspgeratiscrasesvdsyghsfmqwyqqkpgqaprlliyrasnlep
    giparfsgsgsgtdftltisslepedfavyycqqgnevpftfgqgtkveikrtvaapsvf
    ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
    stltlskadyekhkvyacevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records): (download)
    >2nz9C (C:)
    eivltqspatlslspgeratiscrasesvdsyghsfmqwyqqkpgqaprlliyrasnlep
    giparfsgsgsgtdftltisslepedfavyycqqgnevpftfgqgtkveikrtvaapsvf
    ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
    stltlskadyekhkvyacevthqglsspvtksfnrg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2nz9D (D:)
    qvqlqesggglvqpggslrlscaasgftfsdhymywvrqapgkglewvatisdggsytyy
    sdsvegrfttsrdnskntlylqmnslraedtaiyycsryryddamdywgqgtlvtvssas
    tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
    yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkt
    

    Sequence, based on observed residues (ATOM records): (download)
    >2nz9D (D:)
    vqlqesggglvqpggslrlscaasgftfsdhymywvrqapgkglewvatisdggsytyys
    dsvegrfttsrdnskntlylqmnslraedtaiyycsryryddamdywgqgtlvtvssast
    kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2nz9E (E:)
    eivltqspatlslspgeratiscrasesvdsyghsfmqwyqqkpgqaprlliyrasnlep
    giparfsgsgsgtdftltisslepedfavyycqqgnevpftfgqgtkveikrtvaapsvf
    ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
    stltlskadyekhkvyacevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records): (download)
    >2nz9E (E:)
    eivltqspatlslspgeratiscrasesvdsyghsfmqwyqqkpgqaprlliyrasnlep
    giparfsgsgsgtdftltisslepedfavyycqqgnevpftfgqgtkveikrtvaapsvf
    ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
    stltlskadyekhkvyacevthqglsspvtksfnrg
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2nz9F (F:)
    qvqlqesggglvqpggslrlscaasgftfsdhymywvrqapgkglewvatisdggsytyy
    sdsvegrfttsrdnskntlylqmnslraedtaiyycsryryddamdywgqgtlvtvssas
    tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
    yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkt
    

    Sequence, based on observed residues (ATOM records): (download)
    >2nz9F (F:)
    vqlqesggglvqpggslrlscaasgftfsdhymywvrqapgkglewvatisdggsytyys
    dsvegrfttsrdnskntlylqmnslraedtaiyycsryryddamdywgqgtlvtvssast
    kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep