PDB entry 2nz8
View 2nz8 on RCSB PDB site
Description: N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1
Class: signaling protein,cell cycle
Keywords: Trio; Rac1; Dbl-family GEF; Rho-family GTPase; DH/PH cassette
Deposited on
2006-11-22, released
2007-04-10
The last revision prior to the SCOP 1.73 freeze date was dated
2007-06-05, with a file datestamp of
2007-06-28.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.225
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: ras-related C3 botulinum toxin substrate 1 isoform Rac1
Species: HOMO SAPIENS
Gene: RAC1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d2nz8a1 - Chain 'B':
Compound: triple functional domain protein
Species: HOMO SAPIENS
Gene: TRIO
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d2nz8b1, d2nz8b2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2nz8A (A:)
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2nz8B (B:)
gamekrksarrkefimaeliqtekayvrdlrecmdtylwemtsgveeippgivnkeliif
gnmqeiyefhnniflkelekyeqlpedvghcfvtwadkfqmyvtycknkpdstqlileha
gsyfdeiqqrhglansissylikpvqritkyqlllkelltcceegkgeikdglevmlsvp
krandamhlsmlegfdeniesqgelilqesfqvwdpktlirkgrerhlflfemslvfske
vkdssgrskylyksklftselgvtehvegdpckfalwvgrtptsdnkivlkassienkqd
wikhireviqert
Sequence, based on observed residues (ATOM records): (download)
>2nz8B (B:)
arrkefimaeliqtekayvrdlrecmdtylwemtsgveeippgivnkeliifgnmqeiye
fhnniflkelekyeqlpedvghcfvtwadkfqmyvtycknkpdstqlilehagsyfdeiq
qrhglansissylikpvqritkyqlllkelltcceegkgeikdglevmlsvpkrandamh
lsmlegfsqgelilqesfqhlflfemslvfskevkdssgrskylyksklftselgvtehv
egdpckfatsdnkivlkassienkqdwikhireviqert