PDB entry 2ny3

View 2ny3 on RCSB PDB site
Description: HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b
Class: viral protein/immune system
Keywords: HIV, gp120, antibody, CD4, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
Deposited on 2006-11-20, released 2007-02-06
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.205
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2ny3a1
  • Chain 'B':
    Compound: T-cell surface glycoprotein cd4
    Species: Homo sapiens [TaxId:9606]
    Gene: CD4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2ny3b1, d2ny3b2
  • Chain 'C':
    Compound: antibody 17b, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2ny3c1, d2ny3c2
  • Chain 'D':
    Compound: antibody 17b, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2ny3d1, d2ny3d2
  • Heterogens: NAG, SUC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ny3A (A:)
    evvlvnvtenfnmwkndmveqmhediislwdqslkpcvkltplcvgagscntsvitqacp
    kvsfepipihycapagfailkcnnctfngtgpctnvstvqcthgirpvvssqlllngsla
    ceevvirsvnftdnaktiivqlntsveinctgaghcniarakwnntlkqiasklreqfgn
    nktiifkqssggdpeivthwfncggeffycnstqlfnstwfnstwstegsnntegsdtit
    lpcrikqiinmwqkvgkamyappisgqircssnitgllltrdggnsnneseifrpgggdm
    rdnwrselykykvvkie
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ny3A (A:)
    evvlvnvtenfnmwkndmveqmhediislwdqslkpcvkltplcvgagscntsvitqacp
    kvsfepipihycapagfailkcnnctfngtgpctnvstvqcthgirpvvssqlllngsla
    ceevvirsvnftdnaktiivqlntsveinctgaghcniarakwnntlkqiasklreqfgn
    nktiifkqssggdpeivthwfncggeffycnstqlfnstwfnsgsdtitlpcrikqiinm
    wqkvgkamyappisgqircssnitgllltrdggnsnneseifrpgggdmrdnwrselyky
    kvvki
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2ny3B (B:)
    mkkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrr
    slwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltle
    sppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlaf
    qkas
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ny3B (B:)
    kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
    lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
    ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlafq
    k
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ny3C (C:)
    divmtqspatlsvspgeratlscrasesvssdlawyqqkpgqaprlliygastratgvpa
    rfsgsgsgaeftltisslqsedfavyycqqynnwpprytfgqgtrleikrtvaapsvfif
    ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
    ltlskadyekhkvyacevthqglsspvtksfnrg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2ny3D (D:)
    evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
    aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
    gtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
    fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ny3D (D:)
    evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
    aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
    gtlvtvssastkgpsvfplapggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
    ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk