PDB entry 2ny2

View 2ny2 on RCSB PDB site
Description: HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b
Class: viral protein/immune system
Keywords: HIV, gp120, antibody, CD4, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX
Deposited on 2006-11-20, released 2007-02-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: envelope glycoprotein gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ny2a1
  • Chain 'B':
    Compound: T-cell surface glycoprotein cd4
    Species: Homo sapiens [TaxId:9606]
    Gene: CD4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ny2b1, d2ny2b2
  • Chain 'C':
    Compound: antibody 17b, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ny2c1, d2ny2c2
  • Chain 'D':
    Compound: antibody 17b, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2ny2d1, d2ny2d2
  • Heterogens: NAG, EDO, HEZ, SUC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ny2A (A:)
    evvlvnvtenfnmwkndmveqmhediislwdqslkpcvklcplcvgagscntsvitqacp
    kvsfepipihycapagfailkcnnktfngtgpctnvstvqcthgirpvvssqlllngsla
    eeevvirsvnftdnaktiivqlntsveinctgaghcniarakwnntlkqiasklreqfgn
    nktiifkqssggdpeivthwfncggeffycnstqlfnstwfnstwstegsnntegsdtit
    lpcrikqiinmwqkvckamyappisgqircssnitgllltrdggnsnneseifrpgggdm
    rdnwrselykykvvkie
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ny2A (A:)
    evvlvnvtenfnmwkndmveqmhediislwdqslkpcvklcplcvgagscntsvitqacp
    kvsfepipihycapagfailkcnnktfngtgpctnvstvqcthgirpvvssqlllngsla
    eeevvirsvnftdnaktiivqlntsveinctgaghcniarakwnntlkqiasklreqfgn
    nktiifkqssggdpeivthwfncggeffycnstqlfnstwfngsdtitlpcrikqiinmw
    qkvckamyappisgqircssnitgllltrdggnsnneseifrpgggdmrdnwrselykyk
    vvki
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2ny2B (B:)
    mkkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrr
    slwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltle
    sppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlaf
    qkas
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ny2B (B:)
    kkvvlgkkgdtveltctasqkksiqfhwknsnqikilgnqgsfltkgpsklndradsrrs
    lwdqgnfpliiknlkiedsdtyicevedqkeevqllvfgltansdthllqgqsltltles
    ppgsspsvqcrsprgkniqggktlsvsqlelqdsgtwtctvlqnqkkvefkidivvlafq
    k
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ny2C (C:)
    divmtqspatlsvspgeratlscrasesvssdlawyqqkpgqaprlliygastratgvpa
    rfsgsgsgaeftltisslqsedfavyycqqynnwpprytfgqgtrleikrtvaapsvfif
    ppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
    ltlskadyekhkvyacevthqglsspvtksfnrg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2ny2D (D:)
    evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
    aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
    gtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvht
    fpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ny2D (D:)
    evqlvesgaevkkpgssvkvsckasgdtfirysftwvrqapgqglewmgriitildvahy
    aphlqgrvtitadkststvylelrnlrsddtavyfcagvyegeadegeydnngflkhwgq
    gtlvtvssastkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
    sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep